Case Study: Cost-Effectiveness Analysis
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Cost-Effectiveness of Strategies to Reduce Maternal Mortality
This analysis used decision analytic modeling to estimate the health impact, financial costs, and cost-effectiveness (dollars per disability-adjusted years of life averted) of scaling-up coverage of two-dose HPV vaccination of 10 year old girls, and once per lifetime cervical cancer screening of women at age 35, in 50 low- and lower-middle-income countries. Learn more.
Cost-effectiveness acceptability curves summarize the distribution of expected benefits and costs in the context of multivariate uncertainty, but don't distinguish between joint distributions of costs and effects that are correlated but differ in scale. Learn how cost-effectiveness and affordability were both considered for HBV vaccination in the Gambia.
In global health, interventions that impose costs per disability-adjusted life year averted less than three and one times GDP per capita are often considered cost-effective and very cost-effective, respectively. This article explores the conceptual foundation and derivation of these thresholds, and suggests options for improvement. Learn more.
