Impact of HPV Vaccine Strategies
Jane Kim Speaking at Podium

Researchers used mathematical models to compare switching from a 2-dose to a 1-dose HPV vaccine. Results show countries can prevent nearly as many cervical cancer cases with 1 dose while awaiting long-term data.

Aging Risk for Childhood Cancer Survivors
Headshot of Jennifer Yeh (top left), Zachary Ward (bottom right). Abstract art images are pictured as well (top right and bottom left).

The COMPASS model was developed to predict long-term outcomes based on treatment exposures and age-related risks in 5-year survivors of childhood cancer diagnosed and treated between 1970 and 1999. This model provides insight into survivor health risks compared to the general population with a goal of informing coordinated care.

Multicancer Early Detection Tests

The study evaluated the impact of using multicancer early detection tests for cancer control in the US population using a microsimulation model spanning 10 years, finding that such tests could significantly reduce late-stage cancer diagnoses.

Elevated Body Weight in US

Is elevated body weight associated with excess mortality in the United States? Using an empirically calibrated microsimulation model, this analysis finds that excess weight not only has substantial impacts on mortality, but that there are large disparities by state and subgroup.

Reducing Cardiovascular Disease Inequities

This paper uses a microsimulation modeling approach and individual-level data from nationally representative surveys to model the distributional impacts of improving hypertension diagnosis and treatment on cardiovascular disease risk and cases across socioeconomic groups. 

New Models for Cervical Cancer Control

Authors propose a new health decision modeling framework to evaluate novel cervical screening technologies. The framework de-emphasizes previously used cytologic-colposcopic-histologic diagnoses, relying instead on HPV type and duration of infection as the major determinants of model transition probabilities.