Soundbites: Practice and Policy
Selected initiatives, publications and resources that reside at the nexus of research, policy and practice are featured below.
EPIC, a multi-year initiative that launched with primary data collection in 6 countries, works to improve the availability and quality of immunization cost and financing information for low-income countries.
PRIMECare Trial - Argentina
PRIMECare is a cluster-randomized clinical trial assessing the effectiveness of a multicomponent strategy (mHealth screening tools, community health workers, integrated electronic appointment scheduler, point-of-care lipid testing, clinical decision support for medication initiation, SMS reminders and educational messaging) to improve cardiovascular disease management across three provinces.
CISNET Cervical works with NCI to apply mathematical modeling methods to evaluate cost-effectiveness of prevention strategies against cervical cancer and other diseases related to HPV.
Studies to confirm the efficacy of a single HPV vaccine dose, of vaccine durability, and of vaccination modifications are needed, but randomized controlled trials are costly and face logistical and ethical challenges. In this study, the authors demonstrate proof-of-principle that a single-arm design yields valid estimates with similar precision to a randomized controlled trial.
The cost and cost-effectiveness of novel tuberculosis (TB) vaccines, which depend on vaccine price and delivery strategy that vary by country, are needed by developers, manufacturers, and potential purchasers to guide investment decisions. This study estimates future costs, cost-effectiveness, and return on investment for novel TB vaccines in low- & middle-income countries.