Scan brief descriptions of cost-effectiveness analyses conducted by our center community and our decision science colleagues across the globe.

Image of Nicole Campos.

Scaling Cancer Prevention

This analysis used decision analytic modeling to estimate the health impact, costs, and cost-effectiveness of scaling-up HPV vaccination and cervical cancer screening in 50 low- and lower-middle-income countries.

Headshots of Allison Portnoy (top) and Nick Menzies (bottom)

Investment Case for TB Vaccines

CHDS postdoctoral fellow Allison Portnoy and CHDS faculty Nick Menzies led economic analyses for a World Health Organization (WHO) report that describes the full value proposition for new tuberculosis (TB) vaccines. 

Image of Stephen Resch Filming in the GHELI Studio.

Cost-Effectiveness Thresholds

Interventions that impose costs per DALY averted less than 3x and 1x GDP per capita are considered cost-effective and very cost-effective, respectively. This article explores the conceptual foundation and derivation of this threshold.

Value for Money Framework

How can we compare the value-for-money of different early childhood development (ECD) interventions? Using published data the authors compute the relative cost-effectiveness of ECD interventions intended to affect motor, cognitive, language and socioemotional skills. 

Cervical Cancer Screening in Nicaragua

A Monte Carlo simulation model of the natural history of HPV infection and cervical cancer was empirically calibrated to epidemiological data in Nicaragua. After integrating country-specific data on screening costs and test performance, the cost-effectiveness of alternative cervical cancer screening strategies was evaluated.

Rotavirus versus HPV Vaccination

Immunization policymakers at global and local levels need to establish priorities among new vaccines competing for limited resources. This study provides early insight into how the comparative impact of two new vaccines could be assessed in resource-poor settings with respect to affordability, cost-effectiveness, and distributional equity.